Thelansis

  Cocaine intoxication and abuse are characterized by adrenergic hyperactivity and increased blood pressure. Cocaine use is linked to acute hypertension but not chronic hypertension. Severe hypertension has been reported in propranolol-treated subjects due to unopposed peripheral -stimulation. A 40-year-old woman was treated successfully with nitroprusside and captopril for hypertensive encephalopathy caused by cocaine abuse. Cocaine use during pregnancy increases the risk of premature placental abruption and blood pressure elevation, less responsive to standard therapy than pregnancy-induced hypertension. Cocaine use has been linked to sudden death due to various causes, including cardiac arrhythmias, respiratory arrest, status epilepticus, and impaired thermoregulation. Cocaine use during pregnancy increases the risk of placental abruption and emergency cesarean delivery. This medication binds and blocks monoamine reuptake transporters (dopamine, norepinephrine, and serotonin) wi...