Thelansis

  Lymphoma denotes a collective term encompassing over 80 diverse diseases originating from the malignancy of lymphocytes, specifically T cells. T-cell lymphomas, a rare subset of non-Hodgkin lymphomas (NHL), exhibit a spectrum of indolent to aggressive manifestations. The etiology of most T-cell lymphomas remains elusive, with suggested associations involving genetic dysregulation (cancer-testis genes and B lymphoid tyrosine kinase) and aberrant signaling pathways (Jak-3/STAT and NOTCH1). Chronic cutaneous inflammation, such as chronic urticaria and chemical exposure, has been linked to the development of cutaneous T-cell lymphoma (CTCL). Clinical manifestations of T-cell lymphoma encompass chest pain, coughing, difficulty breathing, fever, night sweats, abdominal pain or swelling, persistent fatigue, swollen lymph nodes, and unintentional weight loss. Infectious factors, including bacterial and viral associations (such as retrovirus-like Human T-cell leukemia virus 1 and 2, HIV...