Thelansis

  Hepatoblastoma (HB) is the most common primary malignant liver neoplasm in children 1. In the vast majority of cases, it is associated with elevated alpha-fetoprotein (AFP), which is helpful in diagnosis and monitoring response to treatment as well as the follow-up. HB is associated with excellent survival, in the range of 70–80%, although before the introduction of chemotherapy (CHT), it was below 30%. HB comprises 1% of all pediatric malignancies and primarily affects infants and young children between 6 months and 3 years, but cases in neonates and adolescents have also been reported. After neuroblastoma and nephroblastoma, primary epithelial tumors of the liver are the third most common intraabdominal neoplasms in children.   HB is a liver malignancy with a relatively constant annual incidence of 1.2-1.5 cases per million children younger than 15 in Western countries.   The competitive landscape of Hepatoblastoma (HB) includes country-specific approved and p...

  Hepatoblastoma (HB) is the most common primary malignant liver neoplasm in children 1. In the vast majority of cases, it is associated with elevated alpha-fetoprotein (AFP), which is helpful in diagnosis and monitoring response to treatment as well as the follow-up. HB is associated with very good survival, in the range of 70–80%, although before the introduction of chemotherapy (CHT) it was below 30%. HB comprises 1% of all pediatric malignancies and affects mostly infants and young children between 6 months and 3 years, but cases in neonates and adolescents have also been reported. After neuroblastoma and nephroblastoma, primary epithelial tumors of the liver are the third most common intraabdominal neoplasms in children.   HB is a malignancy of the liver with a fairly constant annual incidence of 1.2-1.5 cases per million children younger than 15 years of age in Western countries.   The competitive landscape of Hepatoblastoma (HB) includes country-specific ap...