Thelansis

 Major depressive disorder (MDD), also known as Depression, is a severe medical condition that disrupts various aspects of a person's life, including mood, behavior, thought processes, and physical well-being. While sadness and grief are normal responses to life's challenges, depression represents a more intense and prolonged state of emotional distress. There are also other related conditions, such as bipolar disorder (manic-depressive illness) and dysthymia. Bipolar disorder is characterized by alternating episodes of depression and mania. During manic episodes, individuals may experience extreme and inappropriate "high" emotions that can lead to risky and destructive behaviors. Dysthymia, on the other hand, exhibits symptoms similar to those of major depressive disorder but typically persists over a longer duration. The decline in hippocampal function is believed to play a role in depression by inhibiting the hypothalamic-pituitary-adrenal (HPA) axis, potentially c...

 Major depressive disorder (MDD), also referred to as depression, is a severe medical illness that disrupts a person’s mood, behavior, thought processes, and physical health. Sadness and grief are normal reactions to life stresses. Other forms include bipolar disorder (manic-depressive illness) and dysthymia. In bipolar disorder, episodes of depression alternate with episodes of mania, a condition in which inappropriate or extreme “high” feelings may lead to dangerous, destructive behavior. Dysthymia involves symptoms similar to those of major depressive disorder. The decline in hippocampal function, which is believed to have an inhibitory effect on the hypothalamic-pituitary-adrenal (HPA) axis, could potentially be responsible for the hypercortisolemia seen in depression. Pro-inflammatory marker levels are reported to be elevated in depressed patients, such as C-reactive protein (CRP), interleukin (IL)-6, IL-1, and tumor necrosis factor-alpha (TNF-α). ·     ...