Thelansis

  Non-Hodgkin lymphoma (NHL) encompasses a spectrum of malignant tumors arising from lymphoid tissues, primarily within the lymph nodes. Chromosomal translocations, exposure to toxins, infections, and persistent inflammation can trigger these tumors. Various factors, such as infections, environmental influences, immunodeficiency conditions, and chronic inflammation, may contribute to the development of NHL. Originating from B, T, or natural killer cells, NHL arises through chromosomal translocation or mutation/deletion events. This process involves the activation of proto-oncogenes via chromosomal translocation and inactivation of tumor suppressor genes through chromosomal deletion or mutation. The t (14;18) translocation is NHL's most prevalent chromosomal abnormality. Diagnosis typically involves serum chemistry tests and imaging studies, typically CT scans of the neck, chest, abdomen, and pelvis or PET scans. Common treatments include chemotherapy, radiotherapy, immunotherapy,...