Thelansis

  Diamond-Blackfan anemia (DBA) is a rare inherited disorder affecting the body's red blood cell production. It typically appears in infancy and is characterized by anemia, which can cause symptoms such as paleness, difficulty feeding, and failure to thrive. About 50% of cases of DBA are caused by mutations in certain genes that produce ribosomal proteins S19, L5, L11, or S26, while mutations in other genes, such as S7, S24, S17, S10, cause a small percentage. In addition to anemia, around 50% of patients with DBA also have congenital malformations, and a higher rate may have premature birth (20%), low birth weight (28%), and growth delays (22%). Most cases are diagnosed in the first few years of life, with 95% diagnosed before age 2 and almost 99% before age 5. However, DBA can sometimes be present at birth or detected during pregnancy. It is important to distinguish DBA from other types of anemia, such as those caused by viral infections or temporary conditions in children. Peo...

 Diamond-Blackfan anemia (DBA) is a rare inherited disorder that affects the body's production of red blood cells. It typically appears in infancy and is characterized by anemia, which can cause symptoms such as paleness, difficulty feeding, and failure to thrive. About 50% of cases of DBA are caused by mutations in specific genes that produce ribosomal proteins S19, L5, L11 OR S26, while mutations in other genes, such as S7, S24, S17, and S10, cause a small percentage. In addition to anemia, around 50% of patients with DBA also have congenital malformations, and a higher rate may have premature birth (20%), low birth weight (28%), and growth delays (22%). Most cases are diagnosed in the first few years of life, with 95% diagnosed before age two and almost 99% before age 5. However, DBA can sometimes be present at birth or detected during pregnancy. It is important to distinguish DBA from other types of anemia, such as those caused by viral infections or temporary conditions in chi...