Thelansis

Low-grade gliomas grade II astrocytomas, oligodendrogliomas, and oligoastrocytomas) are a diverse set of primary brain tumors that are characteristically diffuse and slow growing. Pediatric Low-grade gliomas (pLGG) are relatively slow-growing infiltrative primary brain tumors that almost invariably undergo malignant transformation most common brain tumours in children and can arise from glial cells, neuronal cells or both. This heterogeneity is also reflected in the diverse range of anatomical locations of these tumours within the CNS and in treatment outcomes, especially if surgical resection is either incomplete or not feasible. Low-grade gliomas comprise several subgroups, including pilocytic, pilomyxoid, subependymal giant cell, and diffuse astrocytomas.  Two cancer-predisposition syndromes, neurofibromatosis type 1 (NF1) and tuberous sclerosis complex, are associated with an increased frequency of pilocytic astrocytomas and subependymal giant cell astrocytomas, respectively. E...