Thelansis

  Necrobiosis lipoidica (NL) is a rare chronic granulomatous dermatitis that usually appears in the lower extremities. It affects about 0.3-1.2% of diabetic patients, the majority of whom have type 1 diabetes. The etiology and pathogenesis of this disorder are still unclear. NL is characterized by a skin rash that usually affects the shins. The average onset is 30 years, with females being affected more commonly. There are very few reported cases of necrobiosis lipoidica in children. The legs are the most common site for NLD, but the involvement of other areas, such as the abdomen, upper extremities, and scalp, has been reported. There is no rational therapy. However, benefits have been reported from different treatment regimens, such as drugs acting on the hemostatic mechanisms, corticosteroid therapy (topical, intralesional, and systemic), enhancers of wound healing, surgery, and immunomodulating therapies (including photochemotherapy). Thelansis’s “Necrob...