Thelansis

 Atypical Teratoid Rhabdoid Tumor (ATRT) is an uncommon and highly aggressive embryonal central nervous system (CNS) tumor typically found in children under 3. ATRT carries a grim prognosis, with most pediatric cases having a reported median survival of only 6 to 12 months. These tumors' rapid growth leads to the onset of ATRT symptoms, which can manifest within days or weeks. These symptoms encompass: 1.        Morning headaches upon waking 2.        Hydrocephalus is characterized by an accumulation of brain fluid, potentially causing enlarged heads in infants or headaches and vomiting in older children 3.        Nausea and vomiting are typically worse in the morning and improve throughout the day 4.        Lethargy and fatigue 5.        Balance and coordination difficulties Pathologically, ATRTs display characteristics s...

 Atypical Teratoid Rhabdoid Tumor (ATRT) is a rare and aggressive type of embryonal tumor of the central nervous system (CNS) occurring in childhood, primarily occurring at age of fewer than 3 years. ATRTs are associated with a very poor prognosis, with a reported median survival of 6–12months in most pediatric cases. ATRTs demonstrate pathological findings that are typical of primitive neuroectodermal tumors (PNET), featuring necrosis with a high rate of mitotic activity and the presence of rhabdoid cells. The majority of AT-RTs also demonstrate a loss of INI-1 nuclear staining, ATRTs can form anywhere in the CNS spread to the spinal cord. ATRTs can form outside the CNS, such as in the kidney. ATRTs develop from several different very young cells called embryonal cells. These cells include rhabdoid, neuroepithelial, epithelial, and mesenchymal. Due to the extremely rare incidence of this tumor in adult populations, diagnosis is often delayed given that it falls much lower on the d...

  Atypical teratoid/rhabdoid tumor (ATRT) is a rare and aggressive type of embryonal tumor of the central nervous system (CNS) occurring in childhood, primarily occurring at fewer than three years. ATRTs are associated with an inferior prognosis, with a reported median survival of 6–12months in most pediatric cases. ATRTs demonstrate pathological findings typical of primitive neuroectodermal tumors (PNET), featuring necrosis with a high rate of mitotic activity and rhabdoid cells. Most AT-RTs also show a loss of INI-1 nuclear staining; ATRTs can form anywhere in the CNS spread to the spinal cord. ATRTs can start outside the CNS, such as in the kidney. ATRTs develop from several different very young cells called embryonal cells. These cells include rhabdoid, neuroepithelial, epithelial, and mesenchymal. Due to the infrequent incidence of this tumor in adult populations, diagnosis is often delayed. It falls much lower on the differential diagnosis than other more common tumors. ...