Thelansis

 Cocaine use disorder (CUD) is a significant global public health issue characterized by the compulsive use of cocaine despite its detrimental medical, psychological, and behavioral effects. The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), defines CUD as the presence of at least 2 out of 11 criteria causing clinically significant impairment or distress within 12 months. These criteria can be categorized into four groups: physiological (craving, tolerance, and withdrawal), loss of control, prioritization of cocaine over other activities, and negative consequences resulting from cocaine use. The severity of CUD is determined by the number of symptoms present: mild CUD is indicated by two or three symptoms, moderate CUD by four or five symptoms, and severe CUD by six or more symptoms. Continued cocaine use over time carries a high risk of progressing to CUD, particularly among individuals who initiate cocaine use around the age of 20. This younger popu...