Nephroblastoma – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2022 To 2032

Wilms' Tumor or Nephroblastoma is a rare malignant renal tumor that typically affects children, characterized by abnormal proliferation of cells that resemble embryonic kidney cells (metanephroma), leading to the term embryonal tumor. It mainly affects young children between the ages of 1 and 5 years, although it can occur before the age of 1 year or after the age of 8 years. Adult forms are very rare. The tumor is usually present as an abdominal mass, which is frequently unilateral. Other symptoms may include abdominal pain, hypertension, fever, hematuria, and anemia. The disease progresses rapidly, with regional dissemination in the retroperitoneal space, lymph nodes, vessels (renal vein and inferior vena cava), and the peritoneal cavity in cases of tumor effraction, with a high likelihood of metastases in the lungs and liver. Nephroblastoma is sporadic in 99% of cases, with 10% of these cases associated with congenital anomalies or specific syndromes. Genetic anomalies have bee...