Desmoid Tumor – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Desmoid tumor (DT) is a rare type of monoclonal, fibroblastic proliferation that can have an unpredictable clinical course. The World Health Organization (WHO) classifies DT as a "clonal fibroblastic proliferation that arises in the deep soft tissues and is characterized by infiltrative growth and a tendency toward local recurrence but an inability to metastasize." While DT can occur in multiple areas of the same limb or body part, it typically appears in abdominal, intra-abdominal, and extra-abdominal locations. About 5-10% of DT cases occur in individuals with familial adenomatous polyposis (FAP). CTNNB1 mutations and APC mutations are mutually exclusive in DT. Diagnosis depends on a combination of morphologic and immunohistochemical findings. DT is most often poorly circumscribed on a surgical specimen, featuring a scar-like, whitish-cut surface and ranging in size. Microscopically, a DT is composed of a cytologically bland, at most moderately cellular, infiltrative spind...