Thelansis

  African trypanosomiasis, also referred to as human African trypanosomiasis (HAT) or sleeping sickness, is a disease caused by one of two protozoa, Trypanosoma brucei, transmitted by the tsetse fly in sub-Saharan Africa. This illness falls under the category of neglected tropical diseases and poses a significant threat, as it is often fatal if left untreated. Trypanosoma brucei is typically transmitted to humans through the bite of an infected tsetse fly. Once the tsetse fly acquires the trypanosomes, they undergo multiplication and develop into epimastigotes. Humans become infected following a tsetse fly bite, after which the injected parasites rapidly proliferate in the bloodstream and lymphatic system. Ultimately, the parasite infiltrates the central nervous system (CNS), leading to neurological and behavioral symptoms. In some cases, individuals may experience a severe hypersensitivity reaction to the parasite, resulting in itching, swelling, and edema. To detect HAT caused ...