Thelansis

 Arginase-1 deficiency is a rare inherited disorder characterized by a complete or partial lack of the enzyme arginase in the liver and red blood cells. Arginase is one of six enzymes that play a role in the breakdown and removal of nitrogen from the body, a process known as the urea cycle. The lack of the arginase enzyme results in excessive accumulation of nitrogen, in the form of ammonia (hyperammonemia), in the blood and arginine (hyperuricemia) in the blood and cerebrospinal fluid. Symptoms associated with arginase-1 deficiency differ from those associated with other disorders of the urea cycle. Most infants with an arginase-1 deficiency do not exhibit any symptoms during the first few months to a year of life. Infants with arginase-1 deficiency infrequently experience severe hyperammonemia or hyperammonemia coma, which are characteristic of the other urea cycle disorders. Affected children may experience a lag in growth between one and three years and may walk on their toes a...

 Arginase-1 deficiency is a rare inherited disorder characterized by a complete or partial lack of the enzyme arginase in the liver and red blood cells. Arginase is one of six enzymes that play a role in the breakdown and removal of nitrogen from the body, a process known as the urea cycle. The lack of the arginase enzyme results in excessive accumulation of nitrogen, in the form of ammonia (hyperammonemia), in the blood and arginine (hyperuricemia) in the blood and cerebrospinal fluid. Symptoms associated with arginase-1 deficiency differ from those associated with other disorders of the urea cycle. Most infants with an arginase-1 deficiency do not exhibit any symptoms during the first few months to a year of life. Infants with arginase-1 deficiency infrequently experience severe hyperammonemia or hyperammonemia coma, which are characteristic of the other urea cycle disorders. Affected children may experience a lag in growth between one and three years and may walk on their toes a...

  Arginase-1 deficiency is a rare inherited disorder characterized by a complete or partial lack of the enzyme arginase in the liver and red blood cells. Arginase is one of six enzymes that play a role in the breakdown and removal of nitrogen from the body, known as the urea cycle. The arginase enzyme's lack results in excessive nitrogen accumulation, in the form of ammonia (hyperammonemia), in the blood and arginine (hyperuricemia) in the cerebrospinal blood fluid. Symptoms associated with arginase-1 deficiency differ from those related to other urea cycle disorders. Most infants with an arginase-1 deficiency do not exhibit any symptoms during the first few months to a year of life. Infants with arginase-1 deficiency infrequently experience severe hyperammonemia or hyperammonemia coma, characteristic of the other urea cycle disorders.   Affected children may experience a lag in growth between one and three years and may walk on their toes and develop progressive stiffness and...

  Arginase-1 deficiency is a rare inherited disorder characterized by a complete or partial lack of the enzyme arginase in the liver and red blood cells. Arginase is one of six enzymes that play a role in the breakdown and removal of nitrogen from the body, a process known as the urea cycle. The lack of the arginase enzyme results in excessive accumulation of nitrogen, in the form of ammonia (hyperammonemia), in the blood, and arginine (hyperuricemia) in the blood and cerebrospinal fluid. Symptoms associated with arginase-1 deficiency differ from those associated with other disorders of the urea cycle. Most infants with an arginase-1 deficiency do not exhibit any symptoms during the first few months to a year of life. Infants with arginase-1 deficiency infrequently experience severe hyperammonemia or hyperammonemia coma, which are characteristic of the other urea cycle disorders.  Affected children may experience a lag in growth between one and three years and may walk on thei...