Thelansis

  Primary hyperlipidemias encompass a diverse group of monogenic and polygenic conditions characterized by a familial tendency, severe instances of hypercholesterolemia and hypertriglyceridemia, early onset in life, and a heightened risk of cardiovascular events and recurrent pancreatitis. Individuals affected by these conditions experience lifelong exposure to notably elevated concentrations of atherogenic particles, leading to the development of severe and premature atherosclerosis. In comparison to secondary causes of extreme hypertriglyceridemia, primary hypertriglyceridemias pose a significantly greater risk for recurrent pancreatitis events. Without intervention, these individuals are susceptible to the onset of cardiovascular diseases and acute pancreatitis. Beyond familial hypercholesterolemia (FH), various types of primary hyperlipoproteinemias exist, each clinically significant and categorized based on their associated pathophysiology and genetic abnormalities; familial lip