Eisenmenger Complex – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Eisenmenger Complex is a clinical syndrome resulting from a congenital heart defect characterized by large anatomical shunts. Hemodynamic forces acting on these anatomic abnormalities initially cause a left-to-right shunt, leading to the development of severe pulmonary arterial hypertension (PAH) and increased vascular resistance. Eventually, due to elevated pulmonary vascular resistance, the direction of the shunt reverses, resulting in a right-to-left shunt and subsequent hypoxemia and cyanosis. Eisenmenger syndrome can arise from various heart defects that induce PAH, including atrial septal defects (ASD), ventricular septal defects (VSD), atrioventricular septal defects (AVSD), and patent ductus arteriosus (PDA), as well as more complex cardiac lesions. Unrepaired Tetralogy of Fallot (ToF) can also lead to the development of Eisenmenger syndrome. The most frequently observed defects associated with Eisenmenger syndrome are ASD, VSD, and PDA. The transformation of a left-to-...