Chemoradiation-induced oral mucositis (CRIOM) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030
Oral mucositis is an important complication in non-surgical cancer treatments. It represents the major complication in radiotherapy of tumors located in head and neck areas. Mucositis manifests itself as erythema, edema, or ulceration that can be accompanied by a mild burning sensation. Radiation-induced mucositis may involve any radiation-exposed area, including the hard palate, lip, buccal mucosa, tongue ventrolateral aspect, and base of the mouth. The direct mechanisms of irradiation include interrupting the cell renewal cycle and apoptosis. The indirect mechanisms leading to oral mucositis include the release of inflammation mediators, the loss of protective salivary role, and neutropenia induced by the treatment. · Oropharyngeal mucositis occurs in more than 85 to 92% of patients who receive radiation and or chemotherapy for head and neck tumors. · According to the research, ~85% of patients underg...