Thelansis

  Muscle Spasticity is a velocity-dependent increase in muscle tone or tonic stretch reflexes linked to hypertonia that characterizes spasticity, a motor condition often known as tightness or stiffness. Spasticity is seen as a positive indicator of Upper motor neuron syndrome (UMNS), which is defined as motor behaviors arising from lesions in the brain or spinal cord that are close to the alpha motor neuron. Exaggerated muscular stretch reflexes and upward-moving plantar reflexes are two additional advantageous characteristics of UMNS. Motor weakness, slower movement, loss of dexterity, or selective motor control are examples of negative traits. Baclofen: This increases the overall inhibitory effects within the reflex pathway by acting as a Gamma-Amino Butyric Acid (GABA) agonist at GABA receptors. Tizanidine is an alpha-2 adrenergic agonist that shares chemical similarities with clonidine. It works by strengthening the spinal reflex's presynaptic inhibition. Thelansis’s “Musc...