Thelansis

Dedifferentiated liposarcoma, the rarest form of liposarcoma, typically arises from a well-differentiated liposarcoma (WDLPS). Its progression occurs in 17% of patients when WDLPS is located in the retroperitoneum and 6% when it occurs in the extremities. This condition is characterized as an atypical liposarcoma that changes over time, exhibiting varying histologic grades. It combines the features of a low-grade liposarcoma with those of a high-grade spindle cell sarcoma. This tumor predominantly affects adults beyond their 60s, with a slight male predominance, and is most commonly found in the abdominal cavity. The most frequently observed phenotype resembles pleomorphic malignant fibrous histiocytoma, although other sarcomatous phenotypes have been described less frequently. Surgical intervention is the primary treatment for dedifferentiated liposarcoma. ·        However, it is associated with a reported local recurrence rate of 41% to 52%, a distant met...

  Dedifferentiated liposarcoma is the rarest type of liposarcoma and usually develops from a well-differentiated liposarcoma (WDLPS). Progression occurs in 17% of patients when WDLPS is located in the retroperitoneum and 6% of cases when WDLPS is located in the extremities. It is also defined as an atypical liposarcoma that progresses or changes over time with variable histologic grades. This is essentially a low-grade liposarcoma admixed with a high-grade spindle cell sarcoma. Dedifferentiated account for ~20% of total liposarcoma cases; according to Thelanis disease modeling study, there are ~8200 dedifferentiated liposarcoma cases in the US in the year 2020. Thelansis’s “Dedifferentiated Liposarcoma Market Outlook, Epidemiology, Competitive Landscape , and Market Forecast Report – 2021 To 2032" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market...