Thelansis

  Kaposi’s sarcoma (KS) is a malignant neoplasm of the vascular endothelium that is multifocal, involving the skin and other organs. Based on epidemiological features, four types of Kaposi’s sarcoma have been recognized: classic, endemic, iatrogenic, and epidemic (AIDS related). The course of KS ranges from indolent, with only skin manifestations, to fulminant, with extensive visceral involvement. Because of its broad morphologic spectrum and similarities to many benign vasoproliferative lesions (e.g., microvenular hemangioma, bacillary angiomatosis, and pyogenic granuloma) and tumors with a prominent spindle cell component, KS poses difficulties in histologic diagnosis. The variability in the behavior of KS among individuals in the same group remains enigmatic. Clinically, Kaposi sarcoma is a vascular lesion that frequently manifests as a violaceous pink to purple plaque on the skin or mucocutaneous surfaces. Lesions can be painful, especially if they are associated with lymphed...

 Kaposi’s sarcoma (KS) is a malignant neoplasm of the vascular endothelium that is multifocal, involving the skin and other organs. Based on epidemiological features, four types of Kaposi’s sarcoma have been recognised: classic, endemic, iatrogenic and epidemic (AIDS related). The course of KS ranges from indolent, with only skin manifestations, to fulminant, with extensive visceral involvement. Because of its broad morphologic spectrum and similarities to many benign vasoproliferative lesions (e.g., microvenular hemangioma, bacillary angiomatosis, and pyogenic granuloma) and tumors with a prominent spindle cell component, KS poses difficulties in histologic diagnosis. The variability in the behavior of KS among individuals in the same group remains enigmatic. Clinically, Kaposi sarcoma is a vascular lesion that frequently manifests as a violaceous pink to the purple plaque on the skin or mucocutaneous surfaces. Lesions can be painful, especially if they are associated with lymphed...