Thelansis

Eosinophilic esophagitis is the most commonly recognized EDD. Patients often present with symptoms similar to gastroesophageal reflux disease; however, they are not responsive to traditional antireflux therapy. In fact, there is emerging data to suggest that the use of acid-suppressive medications may predispose patients to the development of eosinophilic esophagitis. The alteration of gastric pH caused by antisecretory medications has been shown to affect protein digestion, allowing a larger percentage of ingested protein to be absorbed in larger fragments, potentially inducing an immunologic response. The diagnosis of eosinophilic esophagitis relies on endoscopic biopsy. Visualization of the esophagus during endoscopy may appear abnormal, including esophageal furrows and strictures, white plaques, or mucosal rings. However, in one-third of patients, the appearance of the esophagus may be normal. The reported incidence is approximately 6.5 to 7.8 cases per 100,000 population. However,...