Thelansis

  Cachexia Syndrome (CS) is a multifactorial syndrome characterized by body weight loss, declining muscle mass and function, wasting, and inflammation of adipose tissues accompanied by metabolic dis-arrangement, anorexia, systemic inflammation, and insulin resistance. The clinical relevance of cachexia is shown by its impact on both the prognosis and the efficacy of treatment against the underlying disease and survival time and quality of life. Cachexia is typically associated with several underlying chronic degenerative diseases, such as cancer, chronic obstructive pulmonary disease (COPD), HIV, chronic heart failure, diabetes, liver failure, rheumatoid arthritis, and chronic kidney failure. Chronic conditions share several underlying mechanisms and ultimately have similar output, i.e., severe muscle wasting. However, the multifactorial origin of cachexia and its multisystem involvement made the study of this syndrome in the context of underlying chronic diseases. This is also cha...