Thelansis

  Adrenal insufficiency (AI) or Addison’s disease is a rare disorder characterized by inadequate cortisol and aldosterone production. The symptoms of classic Addison’s disease, also known as primary adrenal insufficiency, result from the insufficient production of these two hormones, cortisol and aldosterone. Diagnosis measures the adrenal corticosteroid hormones, their regulatory peptide hormones, and stimulation tests. It is classified as primary adrenal insufficiency (PAI) or secondary adrenal insufficiency (SAI). PAI results from intrinsic disease to the adrenal cortex, most commonly due to autoimmune adrenalitis. Due to pituitary disease, SAI is caused by insufficient or deficient corticotropin production. The most common cause of adrenal insufficiency is glucocorticoid-induced adrenal insufficiency (GIAI), a unique form of SAI caused by long-term iatrogenic glucocorticoid use. In the USA, the prevalence of Adrenal insufficiency (AI) ranges between 55  to 140 cases per ...