Thelansis

  Colorectal cancer, also known as colon cancer, appears in the colon or the rectum and is the third leading cause of cancer that develops slowly over several years. It usually begins as a non-cancerous polyp, an abnormal growth of tissue that lines the colon. Colorectal cancer can manifest as sporadic (70%), familial clustering (20%), and inherited syndrome (10%). Several risk factors are associated with colon cancer, including age, environment, diets with high animal fat, obesity, cigarette smoking, heavy alcohol consumption, hereditary, and history of inflammatory bowel disease. The most common type of colon cancer found in patients diagnosed is adenocarcinoma. The adenoma-carcinoma sequence is the base for colorectal cancer development, with a build-up of genetic alteration. The gatekeeper (gene that regulates growth) pathway accounts for approximately 85% of sporadic colorectal cancers and is the mechanism of carcinogenesis in FAP patients. Mutation of the tumor-suppressor gen...

  Colorectal cancer, also known as colon cancer, appears in the colon or the rectum and is the third leading cause of cancer that develops slowly over several years. It usually begins as a non-cancerous polyp, an abnormal growth of tissue that lines the colon. Colorectal cancer can manifest as sporadic (70%), familial clustering (20%), and inherited syndrome (10%). Several risk factors are associated with colon cancer, including age, environment, diets with high animal fat, obesity, cigarette smoking, heavy alcohol consumption, hereditary, and history of inflammatory bowel disease. The most common type of colon cancer found in patients diagnosed is adenocarcinoma. The adenoma-carcinoma sequence is the base for colorectal cancer development, with a build-up of genetic alteration. The gatekeeper (gene that regulates growth) pathway accounts for approximately 85% of sporadic colorectal cancers and is the mechanism of carcinogenesis in FAP patients. Mutation of the tumor-suppressor gen...