Thelansis

  Limb-Girdle Muscular Dystrophy Type 1 (LGMD1A, LGMD1B, LGMD1C, & Others (LGMD1D-H)) includes forms of the disorder that have an inheritance pattern called autosomal dominant. Majorly the LGMD1B comprises more than 65% of the total Limb-girdle muscular dystrophy type 1, followed by LGMD1C, LGMD1A, & Others type. The autosomal dominant forms of LGMD are less common than the autosomal recessive forms and appear later in life. In many cases, autosomal dominant LGMD progresses more slowly than autosomal recessive LGMD and has variable symptoms, even among members of the same family. Each gene mutation can cause a wide range of symptoms. LGMD1A can appear at any age, from adolescence to adulthood. This type of LGMD is distinguished by proximal muscle weakness, which is sometimes accompanied by slurred speech (dysarthria) and an abnormally tight Achilles tendon. LGMD1B causes proximal muscle weakness that gradually worsens. Affected individuals may also experience calf muscle hy...

  Limb-Girdle Muscular Dystrophy Type 1 (LGMD1A, LGMD1B, LGMD1C, & Others (LGMD1D-H)) includes forms of the disorder that have an inheritance pattern called autosomal dominant. Majorly the LGMD1B comprises more than 65% of the total Limb-girdle muscular dystrophy type 1, followed by LGMD1C, LGMD1A, & Others type. The autosomal dominant forms of LGMD are less common than the autosomal recessive forms and appear later in life. In many cases, autosomal dominant LGMD progresses more slowly than autosomal recessive LGMD and has variable symptoms, even among members of the same family. Each gene mutation can cause a wide range of symptoms. LGMD1A can appear at any age, from adolescence to adulthood. This type of LGMD is distinguished by proximal muscle weakness, which is sometimes accompanied by slurred speech (dysarthria) and an abnormally tight Achilles tendon. LGMD1B causes proximal muscle weakness that gradually worsens. Affected individuals may also experience calf muscle hy...