Thelansis

  Hypertrophic cardiomyopathy is a genetic disorder characterized by marked hypertrophy of the myocardium. It is frequently accompanied by dynamic left ventricular outflow tract obstruction and dyspnea, angina, and syncope symptoms. Obstructive Hypertrophic Cardiomyopathy (oHCM) is defined as HCM with left ventricular outflow tract obstruction causing a peak left ventricular outflow gradient of at least 30 mm Hg is observed in approximately 70% of patients with HCM frequently leads to symptoms including dyspnea, fatigue, chest pain, or syncope. The unique pathophysiology underlying the obstruction is its functional dynamic nature, greatly influenced by alterations in the load imposed on the left ventricle and its contractility. The block's initial therapy for symptomatic patients is medical therapy with β-blockers and calcium antagonists. However, a subset of patients have continued severe symptoms, which are unresponsive to medical treatment.   Hypertrophic cardiomyopathy...