Thelansis

  Carcinoid syndrome (CS) is a paraneoplastic syndrome caused by the discharge of serotonin and different substances from well-differentiated neuroendocrine tumors (NETs). CS is a paraneoplastic syndrome associated with the secretion of around 40 vasoactive hormones, the majority of which are 5-hydroxytryptamine (5-HT). CS also involves the secretion of histamine (primary gastric NETs), prostaglandins E and F, kallikrein, and tachykinins. The hallmark symptoms of carcinoid syndrome are diarrhea and flushing; atypical signs and symptoms can include wheezing, pellagra, valvular heart disease, telangiectasias, abdominal pain, and the complications of mesenteric fibrosis, including ureteral obstruction, bowel ischemia, and bowel obstruction. These symptoms are mediated by the release of serotonin (5-HT), prostaglandins, kallikrein, histamine, and tachykinins. These symptoms, as well as the corresponding elevations in lab tests, are required for the diagnosis of CS. Surgery and medica...

Carcinoid syndrome (CS) is a paraneoplastic syndrome caused by the discharge of serotonin and different substances from well-differentiated neuroendocrine tumors (NETs). CS is a paraneoplastic syndrome associated with the secretion of around 40 vasoactive hormones, the majority of which are 5-hydroxytryptamine (5-HT). CS also involves the secretion of histamine (primary gastric NETs), prostaglandins E and F, kallikrein, and tachykinins. The hallmark symptoms of carcinoid syndrome are diarrhea and flushing; atypical signs and symptoms can include wheezing, pellagra, valvular heart disease, telangiectasias, abdominal pain, and the complications of mesenteric fibrosis, including ureteral obstruction, bowel ischemia, and bowel obstruction. These symptoms are mediated by the release of serotonin (5-HT), prostaglandins, kallikrein, histamine, and tachykinins. These symptoms, as well as the corresponding elevations in lab tests, are required for the diagnosis of CS. Surgery and medical manage...