Thelansis

  Idiopathic inflammatory myopathies (IIMs) represent a cluster of autoimmune disorders marked by muscle inflammation (myositis) and involvement of other organs, leading to broad organ dysfunction, heightened morbidity, and premature mortality. Presently, IIMs are categorized into distinct subtypes: Dermatomyositis (DM) includes classic dermatomyositis, juvenile dermatomyositis, and clinical amyopathic dermatomyositis. These may be linked with connective tissue disorders (CTDs) and malignancies. Polymyositis (PM), comprising classical PM and nonspecific or overlap myositis, is often associated with CTDs. Autoimmune necrotizing myopathy, connected with malignancies, statin use, and CTDs. Sporadic IBM is occasionally associated with CTDs. These conditions arise due to prolonged immune activity triggered by exposure to environmental risk factors in individuals with a genetic predisposition. Diagnosing IIM can be straightforward when patients display...