Thelansis

 Prader-Willi Syndrome (PWS) is a rare genetic disorder affecting multiple body systems. It is caused by a deletion of genes on chromosome 15. Infants with PWS have weak muscle tone and feeding difficulties, which can lead to poor weight gain and growth. They also have distinctive facial features. Children with PWS are typically short, have small genitals, develop an excessive appetite, and lack satiety. This can lead to severe obesity if not managed carefully. Other associated endocrine abnormalities include growth hormone deficiency, hypogonadism, hypothyroidism, premature pubarche, and rarely corticotropin deficiency. Cognitive dysfunction is common in PWS, ranging from mild to moderate. Children with PWS may have learning disabilities, impaired speech and language development, and emotional control difficulties. The syndrome may also result in comorbidities such as diabetes, sleep-related breathing disorders, gastrointestinal problems, and infections. Early genetic testing and ...

 Prader-Willi syndrome (PWS) is a genetic disorder due to the loss of function of specific genes. In newborns, symptoms include weak muscles, poor feeding, and slow development. Beginning in childhood, the person becomes constantly hungry, which often leads to obesity and T2D. ·        Patients with Prader-Willi syndrome (PWS) frequently reach adulthood and are able to function in a group home setting, perform vocational work, or attend community college classes. Diminished sensitivity to pain and diminished capacity to vomit may delay the diagnosis of underlying disease ·        According to Thelansis’s research, prevalence at birth is estimated at 1/15,000-30,000 worldwide. Most estimates place the incidence between 1 in 10,000-30,000 individuals in the general population and about 350,000-400,000 individuals worldwide. PWS affects males and females in equal numbers and occurs in all ethnic groups and geographic regi...