Ectodermal Dysplasia (ED) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Ectodermal dysplasias (ED) encompasses over 180 disorders that impact the outer layer of embryonic tissue (ectoderm), which is responsible for forming the skin, sweat glands, hair, teeth, and nails. Additionally, organs like mammary glands, the central nervous system (CNS), external ears, melanocytes, cornea, conjunctiva, and lacrimal apparatus originate from the embryonic ectoderm. Mutations in EDA, EDAR, EDARADD, and WNT10A genes are implicated, with EDA mutations being the predominant cause, contributing to more than half of all cases. Symptoms of ectodermal dysplasias vary depending on the specific type and may differ even within affected families. Common mouth-related issues associated with ED include thinner or softer tooth enamel leading to increased cavities, missing or misshapen teeth, abnormal tooth and jaw positioning, reduced saliva production resulting in dry mouth, and occurrences of cleft lip or palate. Clinical evaluation of a patient exhibiting typical phenotypic ...