Chronic Hepatitis Delta Virus (HDV) Infection – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Hepatitis delta, the most severe form of viral hepatitis in humans, is caused by infection with the hepatitis delta virus (HDV), which stands alone in the genus Deltaviridae. This unique virus relies on the presence of the hepatitis B virus (HBV) for replication, forming a symbiotic relationship. HDV infection produces two forms of an RNA-binding protein, known as the long and small delta antigens (Ag), with the host cell providing essential proteins for replication, notably RNA-directed RNA polymerase activity. Consequently, HDV can only cause disease in individuals who are already infected with HBV. Transmission of HDV primarily occurs through the parenteral route, typically via exposure to contaminated blood or blood products. The hepatitis delta virus expresses a single protein, the hepatitis delta antigen (HDAg), which forms a nucleocapsid-like structure with the viral genome. There are two forms of HDAg: small and large. These antigens and the single-stranded RNA genome are ...