Thelansis

  Acute liver failure (ALF) is a rare and frequently heterogeneous presentation of severe liver dysfunction in a patient with no prior history of liver disease. Despite its high morbidity and mortality, survival has improved due to advances in intensive care management and emergency liver transplantation. Hepatitis A and E are the leading causes of liver failure, with most cases occurring in developing countries. Drug-induced hepatitis accounts for nearly half of all ALF cases in the United States, with acetaminophen being the most common cause. Hepatitis B infection may result in liver failure due to both acute conditions and reactivation of hepatitis B following the start of immunosuppressive therapy. Co-infection with hepatitis B and C may result in ALF, though this is uncommon with hepatitis C alone. Herpes simplex virus, Epstein-Barr virus (EBV), Parvoviruses, cytomegalovirus (CMV), adenovirus, and varicella-zoster virus are all viral etiologies of ALF. The incidence of Ac...