Thelansis

  Nephrotic syndrome (NS) is one of the most common chronic kidney diseases in children and is characterized by significant proteinuria, hypoalbuminemia, and edema. The primary, idiopathic form of NS, which accounts for a large portion of NS, often occurs due to a stale infection in infancy/early childhood. The current recommended treatment is cortisone therapy over multiple weeks. Youth NS can be congenital, presenting within the first three months of life. In these children, there is usually a genetic mutation affecting either the podocyte of the glomerular basement membrane, although rarely it can be associated with congenital infections such as cytomegalovirus. Apart from the hereditary form of nephrotic syndrome, many underlying aetiologies can cause nephrotic syndrome, including glomerular disorders, vasculitides, infections, toxins, malignancy, genetic mutations, and most commonly, unknown.   The incidence of NS varies in different population groups and is currently...