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Showing posts with the label Epilansis

Eye Pain – Emerging Therapy, with Unmet Needs and TPP Insights Report – 2026

Eye Pain Emerging Therapy and TPP Insights Thelansis’s “Eye Pain Emerging Therapy, with Unmet Needs and TPP Insights Report – 2026″ provides a comprehensive analysis of the emerging competitive landscape, unmet needs, target product profiles (TPPs), trial designs, and KOL insights on key emerging therapies and key drug development opportunities in the indication . Eye Pain Overview Eye pain is a complex, non-specific clinical symptom rather than a distinct disease entity, arising from the noxious stimulation of ophthalmic trigeminal pathways due to corneal surface damage, intraocular inflammation, or elevated pressure. Key manifestations range from photophobia and epiphora to referred neuropathic dysesthesia. Diagnosis requires distinguishing distinct ocular pathologies via slit-lamp biomicroscopy, tonometry to measure intraocular pressure (IOP), and fluorescein staining to map epithelial defects. Rather than utilizing a generic triage approach, modern ophthalmic pharmacology targets t...

Locally Advanced or Metastatic HR+/HER2- Breast Cancer – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2026 To 2036

Locally Advanced or Metastatic HR+/HER2- Breast Cancer Market Outlook Thelansis’s “Locally Advanced or Metastatic HR+/HER2- Breast Cancer Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2026 To 2036” covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Locally Advanced or Metastatic HR+/HER2- Breast Cancer treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China). Key business questions answered: How  can drug development and lifecycle management strategies be optimized across G8 markets (US, EU5, Japan, and China)? How large is the patient population in terms of incidence, prevalence, segments, and those receiving drug treatments? What is the 10-year market outlook ...

Asthma – Emerging Therapy, with Unmet Needs and TPP Insights Report – 2026

Asthma Emerging Therapy and TPP Insights Thelansis’s “Asthma Emerging Therapy, with Unmet Needs and TPP Insights Report – 2026″ provides a comprehensive analysis of the emerging competitive landscape, unmet needs, target product profiles (TPPs), trial designs, and KOL insights on key emerging therapies and key drug development opportunities in the indication . Key business questions answered: Detailed emerging competitive landscape Pipeline analysis Target patients for emerging therapies Key companies Key mechanism of actions Launch date estimates, etc. Clinical trial landscape analysis Target patient segments Trial endpoints Trial design Recruitment criteria, etc. Unmet Needs and Opportunities Performance of key current therapies Top areas of unmet needs Opportunity sizing for key unmet needs Target Product Profiles Attributes and levels Physician like...

Asthma – Epidemiology Insights and Forecast Report – 2020 To 2040

Asthma Epidemiology Insights Thelansis’s “ ⁠ Asthma Epidemiology Insights and Forecast Report – 2020 To 2040 ″  provides an analysis of disease burden, characterized by disease definition, prevalence, incidence, diagnosed cases, severity, comorbidities, and clinical manifestations. Potential patient flow dynamics in disease burden are driven by shifts in demographic indicators and their correlation with age and gender distribution over time. Changes in the reported cases and long-term survival of patients may depend on diet, lifestyle, comorbid conditions, and the availability of interventions or therapies. Key business questions answered: 20-year historical and forecast data (2020–2040) Disease definition based on globally accepted and latest criteria (e.g., ICD-10 codes) Granular patient population coverage by year and geography Detailed segmentation by age, gender, subpopulations, comorbidities, line of therapies, etc. Patient funnels ...

Alport Syndrome – Market Access and Reimbursement Insights Report – 2026

Alport Syndrome Market Access and Reimbursement Insights Thelansis’s “Alport Syndrome Market Access and Reimbursement Insights Report – 2026″ provides comprehensive payer insights on the current and evolving market access and reimbursement environments for branded and emerging drugs in the indication. Our team understands the criticality of payer research and insights generation, as well as their importance during drug development, pre-market launch strategy, and post-marketing activities. Alport Syndrome Overview Alport Syndrome is a hereditary nephropathy caused by COL4A3, COL4A4, or COL4A5 mutations disrupting type IV collagen, leading to glomerular basement membrane instability, progressive nephron loss, and sensorineural hearing impairment. It presents with microscopic hematuria, proteinuria, declining eGFR, and bilateral high-frequency hearing loss. Diagnosis combines electron microscopy showing GBM lamellation with genetic confirmation; proteinuria burden and eGFR...

Asthma – Emerging Therapy, with Unmet Needs and TPP Insights Report – 2026

Asthma Emerging Therapy and TPP Insights Thelansis’s “Asthma Emerging Therapy, with Unmet Needs and TPP Insights Report – 2026″ provides a comprehensive analysis of the emerging competitive landscape, unmet needs, target product profiles (TPPs), trial designs, and KOL insights on key emerging therapies and key drug development opportunities in the indication . Asthma Overview Asthma is a chronic inflammatory airway disease characterised by variable, reversible airflow obstruction, bronchial hyperresponsiveness, and airway remodelling, driven predominantly by Th2-mediated eosinophilic inflammation — with type 2 cytokines IL-4, IL-5, and IL-13 central to its pathobiology — alongside non-eosinophilic neutrophilic and mixed phenotypes recognising asthma’s considerable biological heterogeneity. Genetic susceptibility, allergen sensitisation, respiratory viral infections, occupational exposures, and obesity interact as key disease determinants. Patients present with episodic wheeze, dyspnoea...

Advanced or Metastatic Adenoid Cystic Carcinoma (ACC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2025 To 2035

Advanced or Metastatic Adenoid Cystic Carcinoma (ACC) Market Outlook Thelansis’s “Advanced or Metastatic Adenoid Cystic Carcinoma (ACC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2025 To 2035” covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Advanced or Metastatic Adenoid Cystic Carcinoma (ACC) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China). Advanced or Metastatic Adenoid Cystic Carcinoma (ACC) Overview Advanced or metastatic adenoid cystic carcinoma (ACC) is a rare, slow-growing but relentlessly progressive malignancy arising predominantly from salivary glands — major and minor — and occasionally from lacrimal glands, tracheobronchial tree, and breast, characterised by insidious...

Global ⁠Asthma – Epidemiology Insights and Forecast Report (Top 32 Markets) – 2020 To 2040

Global ⁠ Asthma Epidemiology Insights Thelansis’s “Global ⁠ Asthma Epidemiology Insights and Forecast Report (Top 32 Markets) – 2020 To 2040″ provides an analysis of disease burden, characterized by disease definition, kidney biopsy cases, prevalence, incidence, diagnosed cases, severity, comorbidities, and clinical manifestations. Potential patient flow dynamics in disease burden are driven by shifts in demographic indicators and their correlation with age and gender distribution over time. Changes in the reported cases and long-term survival of patients may depend on diet, lifestyle, comorbid conditions, and the availability of interventions or therapies for the 32 markets (North America, Europe, Middle East, Asia Pacific, Africa, South / Latin America). Key business questions answered: 20-year historical and forecast data (2020–2040) Disease definition based on globally accepted and latest criteria (e.g., ICD-10 codes) Granular patient population coverage ...

Acromegaly – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2025 To 2035

Acromegaly Market Outlook Thelansis’s “ ⁠ Acromegaly Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2025 To 2035 ”  covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential ⁠ Acromegaly treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China) . Key business questions answered: How can drug development and lifecycle management strategies be optimized across the 32 markets (North America, Europe, Middle East, Asia Pacific, Africa, South / Latin America)? How large is the patient population in terms of incidence, prevalence, segments, and those receiving drug treatments? What is the 10-year market outlook for sales and patient share? Which events will have the greate...

Osteosarcoma – Market Access and Reimbursement Insights Report – 2026

Osteosarcoma Market Access and Reimbursement Insights Thelansis’s “Osteosarcoma Market Access and Reimbursement Insights Report – 2 026 ″ provides comprehensive payer insights on the current and evolving market access and reimbursement environments for branded and emerging drugs in the indication. Our team understands the criticality of payer research and insights generation, as well as their importance during drug development, pre-market launch strategy, and post-marketing activities . Key business questions answered: Market access and reimbursement for current therapies Coverage on plans Market access restrictions Rebates and contracting Factors influencing formulary access HEOR requirements and influence, etc. Expected market access and reimbursement for key emerging therapies Level of awareness Anticipated coverage on plans Factors that would improve market access Pricing, etc. ...

Breast Cancer – Market Access and Reimbursement Insights Report – 2025

Breast Cancer Market Access and Reimbursement Insights Thelansis’s “Breast Cancer Market Access and Reimbursement Insights Report – 2025″ provides comprehensive payer insights on the current and evolving market access and reimbursement environments for branded and emerging drugs in the indication. Our team understands the criticality of payer research and insights generation, as well as their importance during drug development, pre-market launch strategy, and post-marketing activities . Key business questions answered: Market access and reimbursement for current therapies Coverage on plans Market access restrictions Rebates and contracting Factors influencing formulary access HEOR requirements and influence, etc. Expected market access and reimbursement for key emerging therapies Level of awareness Anticipated coverage on plans Factors that would improve market access Pricing, etc. ...

How Thelansis Supported a Mid-Sized Biopharma Company in Out-Licensing Their Novel IPF Asset

Introduction: During 2024, a mid-sized biopharma company from the European region was developing a novel systematic therapy for the treatment of IPF, seeking an evidence-backed structured partnership strategy, where EpiLansis played an instrumental role in validating the market assumptions, estimating the market potential, and identifying the right licensing partners across the US, EU, and Asia. The company had generated promising Phase 1 safety data in 78 healthy volunteers and a small exploratory efficacy readout in a 26-patient cohort but lacked the internal bandwidth and commercial foresight to identify suitable partners, build a value narrative, and quantify the market opportunity across geographies. Objective: The engagement focused on four quantifiable outcomes: Size the commercial opportunity using updated epidemiology—providing market estimates for 15 geographies covering ~82% of the global IPF market. Map and benchmark 70+ competitive and pipeline...

Neuropathic Pain – Epidemiology Insights and Forecast Report – 2020 To 2040

Neuropathic Pain Epidemiology Insights Thelansis’s “Neuropathic Pain Epidemiology Insights and Forecast Report – 2020 To 2040″ provides an analysis of disease burden, characterized by disease definition, prevalence, incidence, diagnosed cases, severity, comorbidities, and clinical manifestations. Potential patient flow dynamics in disease burden are driven by shifts in demographic indicators and their correlation with age and gender distribution over time. Changes in the reported cases and long-term survival of patients may depend on diet, lifestyle, comorbid conditions, and the availability of interventions or therapies. Key business questions answered: 20-year historical and forecast data (2020–2040) Disease definition based on globally accepted and latest criteria (e.g., ICD-10 codes) Granular patient population coverage by year and geography Detailed segmentation by age, gender, subpopulations, comorbidities, line of therapies, etc. Pati...

Osteosarcoma – Epidemiology Insights and Forecast Report – 2020 To 2040

Osteosarcoma Epidemiology Insights Thelansis’s “Osteosarcoma Epidemiology Insights and Forecast Report – 2020 To 2040″ provides an analysis of disease burden, characterized by disease definition, prevalence, incidence, diagnosed cases, severity, comorbidities, and clinical manifestations. Potential patient flow dynamics in disease burden are driven by shifts in demographic indicators and their correlation with age and gender distribution over time. Changes in the reported cases and long-term survival of patients may depend on diet, lifestyle, comorbid conditions, and the availability of interventions or therapies. Key business questions answered: 20-year historical and forecast data (2020–2040) Disease definition based on globally accepted and latest criteria (e.g., ICD-10 codes) Granular patient population coverage by year and geography Detailed segmentation by age, gender, subpopulations, comorbidities, line of therapies, etc. Patient funnels ...

Bipolar Disorder – Epidemiology Insights and Forecast Report – 2020 To 2040

Bipolar Disorder Epidemiology Insights Thelansis’s “Bipolar Disorder Epidemiology Insights and Forecast Report – 2020 To 2040″ provides an analysis of disease burden, characterized by disease definition, prevalence, incidence, diagnosed cases, severity, comorbidities, and clinical manifestations. Potential patient flow dynamics in disease burden are driven by shifts in demographic indicators and their correlation with age and gender distribution over time. Changes in the reported cases and long-term survival of patients may depend on diet, lifestyle, comorbid conditions, and the availability of interventions or therapies. Key business questions answered: 20-year historical and forecast data (2020–2040) Disease definition based on globally accepted and latest criteria (e.g., ICD-10 codes) Granular patient population coverage by year and geography Detailed segmentation by age, gender, subpopulations, comorbidities, line of therapies, etc. Pati...

Dyslipidemia – Market Access and Reimbursement Insights Report – 2025

Dyslipidemia Market Access and Reimbursement Insights Thelansis’s “Dyslipidemia Market Access and Reimbursement Insights Report – 2025″ provides comprehensive payer insights on the current and evolving market access and reimbursement environments for branded and emerging drugs in the indication. Our team understands the criticality of payer research and insights generation, as well as their importance during drug development, pre-market launch strategy, and post-marketing activities. Dyslipidemia Overview Dyslipidemia is a metabolic disorder characterized by persistent imbalances in blood lipid levels, specifically involving elevated low-density lipoprotein (LDL) cholesterol, increased triglycerides, or pathologically low high-density lipoprotein (HDL) cholesterol. This condition serves as a primary driver of atherosclerosis, where lipid deposits and fibrous plaques narrow the arterial walls, progressively restricting blood flow to vital organs. While often asymptomatic ...