Thelansis

 Mycosis Fungoides (MF) is characterized by the proliferation of epidermotropic, cerebriform T cells. MF lesions present in the form of patches and plaques and may eventually develop tumors and leave the skin to involve peripheral blood, lymph nodes, and viscera. MF lesions are eczematous patches with well-defined borders and appear primarily on non-sun-exposed areas. It is mainly neoplasia of lymphocytes, generally of the CD4+ phenotype, and a cytokine production pattern with a Th2 profile. Other significant phenotypes associated with typical MF are CD8+, CD56+ and the double negative, CD4-and CD8-. Classic MF follows some clinical stages used to identify the disease and its staging. Diagnosis is difficult in the early phases, and the disease mimics different clinical conditions, such as chronic eczema, psoriasis, parapsoriasis, sclero-atrophic lichen, chronic lichenoid pityriasis, pityriasis alba, atopic dermatitis, leprosy, chloracne (MF follicular subtype) and, by analogy, thos...

  Mycosis Fungoides (MF) is characterized by the proliferation of epidermotropic, cerebriform T cells. MF lesions present in the form of patches and plaques and may eventually develop tumors and leave the skin to involve peripheral blood, lymph nodes, and viscera. MF lesions are eczematous patches with well-defined borders and appear primarily on non-sun-exposed areas. It is mainly neoplasia of lymphocytes, generally of the CD4+ phenotype, and a cytokine production pattern with a Th2 profile. Other significant phenotypes associated with typical MF are CD8+, CD56+ and the double negative, CD4-and CD8-. Classic MF follows some clinical stages used to identify the disease and its staging. Diagnosis is difficult in the early phases, and the disease mimics different clinical conditions, such as chronic eczema, psoriasis, parapsoriasis, sclero-atrophic lichen, chronic lichenoid pityriasis, pityriasis alba, atopic dermatitis, leprosy, chloracne (MF follicular subtype) and, by analogy, tho...