Thelansis

  Plague, a severe bacterial infection caused by the Gram-negative microorganism Yersinia pestis, exhibits two primary clinical forms: bubonic plague, marked by painful inflammation of lymph nodes referred to as "buboes," accompanied by elevated body temperature and altered health condition, and pulmonary plague, which presents as chest discomfort, a cough producing bloody phlegm, heightened body temperature, changes in clinical state, and disturbances in consciousness. Plague transmission from animals to humans is facilitated by fleas, with rodents acting as the disease reservoir. Additionally, human-to-human transmission occurs through respiratory pathways. Diagnosis hinges on isolating the bacterium from buboes, blood, or respiratory secretions or through serological testing. Multiple classes of antibiotics have proven effective in combating Yersinia pestis, including aminoglycosides, tetracyclines, cotrimoxazole, rifampicin, fluoroquinolones, and others. Left untreated,...