Thelansis

  Microsatellite stability status in colorectal cancer is both a prognostic and a predictive biomarker that has significant importance in diagnosis and treatment. Microsatellite stability testing confirms whether the DNA segments have several or a few mutations. This helps determine the therapy and clinical practice, such as conventional chemotherapy drugs or immune checkpoint blockade with immunotherapy drugs, which may be more or less effective against a particular colorectal cancer. Colorectal cancer, commonly known as colon cancer, primarily arises in the colon or rectum; it is the third most prevalent form of cancer known for its slow progression over many years. Typically, it originates as a non-malignant polyp, an unusual tissue growth lining the colon. There are three main presentations of colorectal cancer: sporadic (70%), familial clustering (20%), and inherited syndrome (10%). Various risk factors are linked to the development of colon cancer, including age, environmen...