Thelansis

  Osteoarthritis (OA) is a complex condition characterized by progressive musculoskeletal pain and restricted movement, often accompanied by the deterioration of articular cartilage, changes in local bone structure, and the development of osteophytes. This joint disorder manifests differently between men and women, highlighting the importance of recognizing gender dimorphism for both prevention and treatment strategies. These structural and anatomical distinctions can be observed early and later in life, such as the thinner articular cartilage in the distal femur of girls and women compared to boys and men, leading to joint pain, capsule thickening, and osteophyte formation. Approximately 43.3% of individuals experience persistent pain, aching, or stiffness associated with osteoarthritis. The FDA has approved several drugs for the management of osteoarthritis, including Duexis (ibuprofen and famotidine), Mobic (meloxicam), Naprelan (naproxen sodium), Pennsaid (diclofenac sodium t...