Thelansis

  Kounis Syndrome, characterized by the simultaneous occurrence of acute coronary syndromes like coronary spasm, acute myocardial infarction, and stent thrombosis, is linked to conditions involving mast-cell and platelet activation in conjunction with an array of inflammatory cells, such as macrophages and T-lymphocytes. The syndrome arises due to the release of inflammatory mediators such as histamine, arachidonic acid products, platelet-activating factor, neutral proteases, and various cytokines and chemokines during allergic activation. The triggers for Kounis syndrome encompass a broad spectrum, including diverse foods, an assortment of drugs, environmental exposures, and various medical conditions. Modern tools such as cardiac magnetic resonance imaging and myocardial scintigraphy have greatly aided the diagnostic process. Treatment typically involves the administration of intravenous corticosteroids like hydrocortisone at a dose of 1–2 mg/kg/day, along with H1 and H2 antihi...