Thelansis

  Pneumoconiosis is any lung condition caused by inhaling organic or inorganic airborne dust and fibers. Typically encountered in occupational settings, where patients are exposed to such particulates, it is classified as an occupational disease. The commonly encountered forms of pneumoconiosis include asbestosis, silicosis, and coal miner's lung. These conditions lead to inflammation and fibrosis within the lung, leading to irreversible lung damage. Prevention relies on effectively managing workplace exposure and adhering to health and safety regulations. The condition initiates with an inflammatory reaction to inhaled foreign particles, stimulating macrophages, lymphocytes, and epithelial cells. These cells subsequently release various inflammatory mediators such as interleukin-1 beta, TNF-alpha, matrix metalloproteinases, and transforming growth factor-beta. Fibroblasts are then activated to proliferate and encapsulate the dust particles, forming nodules. C...