Thelansis

  Pancreatic adenocarcinoma is a highly aggressive form of cancer that originates from the cells lining the pancreatic ducts. Most cases of pancreatic cancer are classified as adenocarcinomas. At the time of diagnosis, the distribution of pancreatic cancer patients is approximately as follows: 20% with resectable tumors, 30% with locally advanced tumors, and 50% with metastatic disease. Locally advanced pancreatic cancer (LAPC) refers to a subgroup of patients who have pancreatic tumors that are deemed unresectable but have not yet spread to distant sites. These tumors exhibit certain characteristics that make them unsuitable for surgical removal, such as encasement of the superior mesenteric artery or coeliac axis of more than 180 degrees, unreconstructable superior mesenteric vein/portal vein occlusion, aortic involvement, or nodal involvement beyond the field of resection. The prognosis for LAPC patients falls between that of resectable and metastatic patients, with a median o...