Thelansis

 Nonalcoholic fatty liver disease (NAFLD) is characterized by fat accumulation within the liver. A more severe variant of NAFLD is known as nonalcoholic steatohepatitis (NASH), which leads to liver inflammation and damage. NASH typically develops in individuals who are overweight or obese have diabetes, high cholesterol, or elevated triglyceride levels. Nevertheless, some individuals may develop NASH even without these risk factors. NASH progresses through three distinct stages:   Stage 1, called compensated cirrhosis or NASH without fibrosis, denotes a stage where the liver's function remains intact despite some compromise. The liver exhibits slight enlargement, inflammation, and fat accumulation exceeding 5% (steatosis). Stage 2, known as NASH with fibrosis, encompasses the features of Stage 1 and involves the development of liver scarring (fibrosis). This fibrosis stage has four degrees, with Stage 2 corresponding to fibrosis levels 1 to 3. Stage 3 signifies the sever...

 Non-alcoholic steatohepatitis (NASH) is a severe form of non-alcoholic fatty liver disease (NAFLD) where the liver becomes inflamed due to fat accumulation. NASH can progress to include scarring (fibrosis/cirrhosis), preventing the liver from functioning properly. Since the disease comes with few or no symptoms, it can go unnoticed for decades. As fibrosis worsens, cirrhosis develops, and the liver becomes permanently damaged and is no longer able to work properly. Patients generally feel well in the early stages and only begin to have symptoms such as fatigue, weight loss, and weakness—once the disease is more advanced or cirrhosis develops. NASH is usually first suspected after elevations of liver enzymes in routine blood tests are found. A liver biopsy is needed to distinguish NASH from simple fatty liver. ·        NAFLD is highly prevalent in all continents, but the highest rates are reported from South America (31%) and the Middle East (32%), f...