Thelansis

  Polyarticular Juvenile Idiopathic Arthritis (PJIA), a rare form of juvenile idiopathic arthritis, is characterized by the persistence of arthritis that begins before age 16 and affects at least five joints for more than six weeks within the first six months of onset. This subgroup can be divided into two categories: one with a positive rheumatoid factor (RF) test and the other with a negative RF test. The former requires at least two RF positive tests, spaced at least 3 months apart during the initial 6-month period. Both subgroups are more prevalent among girls and may present with mild fever, weight loss, anemia, moderate hepatosplenomegaly, and mild growth retardation. Children diagnosed with polyarticular JIA often face a more challenging disease course than those with fewer affected joints. Their prolonged active disease course increases their risk of joint damage, leading to poorer functional outcomes and reduced quality of life. Key indicators of a poor prognosis for pol...