Thelansis

 Uterine serous carcinoma (USC) typically develops on the surface of endometrial polyps within an atrophic endometrium background. Representing around 10% of all endometrial cancers, USC stands as the foremost non-endometrioid subtype. In contrast, endometrioid carcinoma constitutes the predominant histological subtype, accounting for 85-90% of cases, generally carrying a lower risk of progression and a favorable prognosis, especially for low-grade presentations. Microscopically, USC exhibits distinctive features, including papillae with or without a fibrovascular core, pronounced nuclear atypia, slit-like spaces, solid growth patterns, and scant cytoplasm. Despite ranking as the second most prevalent endometrial cancer type, USC remains relatively uncommon. Patients diagnosed with USC tend to present at an earlier stage compared to those with endometrioid subtype cancer. However, they face heightened risks of relapse and generally have a poorer prognosis when matched stage-for-sta...

 Uterine serous carcinoma (USC) commonly arises on the surface of endometrial polyps in the background of an atrophic endometrium. The most representative non-endometrioid endometrial carcinoma is uterine serous carcinoma (USC), which accounts for about 10% of all endometrial cancers. Endometrioid carcinoma of the endometrium is the most common histological subtype of endometrial cancer, accounting for 85 - 90% of cases and is generally associated with a lower risk for progression and favorable prognosis particularly for low-grade disease. USC is microscopically characterized by (1) papillae with or without a fibrovascular core, (2) marked nuclear atypia, (3) slit-like spaces, (4) solid growth, and (5) scant cytoplasm. Despite being the second most common type of endometrial cancer, USC is still considered a relatively rare tumor. Patients with USC are often diagnosed at an earlier disease stage compared to endometrioid subtype endometrial cancer but remain at a higher risk for rel...