Thelansis

  Gastroesophageal junction adenocarcinoma is a carcinoma in which the epicenter of the tumor is located within the GEJ region and remains a significant clinical problem that increases the disease burden with a poor prognosis. Most patients present with advanced disease, and less than 50% undergo curative treatment. Tumor infiltration of the proximal or distal resection margin has diminished survival in most series. The Siewert classification is applied to adenocarcinomas located within 5 cm above or below the GEJ. The GEJ adenocarcinomas are classified into three types as follows. Type I, which is located 1–5 cm above the GEJ, is adenocarcinoma of the distal esophagus. Type II is true carcinoma of cardia centered between 1 cm above and 2 cm below the GEJ. Type III is subcardial carcinoma located 2–5 cm below the GEJ. Adenocarcinoma of the gastroesophageal junction (GEJ) remains a significant clinical problem increasing in incidence and is associated with a poor prognosis. Most patient