Thelansis

  Psoriasis is primarily an inflammatory skin condition characterized by reactive abnormal epidermal differentiation and hyperproliferation that affects 2-3% of the world's population. The pathophysiology of the disease is primarily characterized by the activation and migration of T-cells to the dermis, which results in the release of cytokines (tumor necrosis factor-alpha, TNF-alpha in particular) that cause inflammation and rapid skin cell production. It can cause many signs and symptoms, including dry, thick, and raised patches on the skin covered with a silvery-white coating called scale, and they can tend to itch. Itching can be especially severe in certain areas, such as the scalp, lower legs, and groin. When Psoriasis affects the hands and feet, painful fissures or cracks can form, requiring the use of one's hands and walking. Severe Psoriasis on the body can also create painful fissures and can bleed. It is considered the most prevalent autoimmune disease caused by inap...