Thelansis

 Sjögren syndrome (SS) is a gradually progressing autoimmune disorder with various organ-specific and systemic symptoms. In SS patients, B-cell activation is consistently observed, leading to the infiltration of B and T cells into target organs, resulting in damage. The typical SS patient, most commonly perimenopausal women, experiences reduced lacrimal and salivary gland function symptoms. Common manifestations include dry mouth (xerostomia), dry eyes (keratoconjunctivitis sicca), and enlargement of the parotid glands. The oral dryness experienced by SS patients can significantly impact their quality of life, interfering with basic daily activities like eating, speaking, and sleeping. The reduction in salivary volume also reduces saliva's natural antibacterial properties, increasing the risk of infections, tooth decay, and periodontal disease. SS patients often complain of ocular discomfort, including itching, grittiness, soreness, and dryness, despite the outward appearance of no...