Thelansis

  Opioid-induced constipation (OIC) is defined as new or worsening of constipation symptoms after initiating, increasing, or modifying opioid therapy and is common in patients on chronic opioid therapy.   Etiology- OIC is primarily mediated through the effects of opioids on μ-receptors in the gastrointestinal tract, reducing bowel tone, contractility, and luminal fecal moisture.   Epidemiology- The prevalence of opioid-induced constipation (OIC) was 12.6%. Opioid-induced constipation (OIC) accounts for over 40% to 60% of patients without cancer receiving opioids.   The competitive landscape of Opioid-Induced Constipation (OIC) includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are being tracked and supplemented with analyst commentary. KOLs insights of Opioid-Induced Constipation (OIC) across 8 MM market from the centre of Excellence/ Public/ Private hospitals ...