Thelansis

Stomach cancer, also known as gastric cancer, is a malignancy that originates from the stomach lining. It is a slow-growing cancer and is considered a multifactorial disease. The International Agency for Research on Cancer (IARC) has classified the bacterium Helicobacter pylori (H. pylori) as a carcinogen in humans due to the evidence linking H. pylori infection and an increased risk of gastric cancer. The mechanism by which H. pylori acts as a carcinogen is believed to be indirect, through the induction of gastritis, which can lead to the development of precancerous conditions such as gastric atrophy, metaplasia, and dysplasia. Individuals with certain genetic disorders, such as hereditary diffuse gastric cancer, Peutz-Jeghers syndrome, and familial adenomatous polyposis, have an increased risk of developing stomach cancer. Mutations or deletions in genes such as p53, BRCA2, MSH2, and MLH1 also increase the risk of gastric cancer. The symptoms of stomach cancer can be classified into ...