Thelansis

 Skin Burn is a thermal injury caused by biological, chemical, electrical, and physical agents, with local and systemic consequences; it is the most severe form of trauma that has afflicted humanity since time immemorial. Its treatment has improved over time with the scientific revolution. To provide appropriate treatment, the patient's approach must be multidisciplinary; however, in the first instance, the entire body surface must be quantified, not just the percentage but also the depth. Once the clinical classification of burns by depth is understood, these are manifested with characteristic lesions that assist us in recognizing them practically. TNF-α also involves the antimicrobial defenses by activation of neutrophils and monocytes and can induce the secretion of other proinflammatory mediators, including IL-1 and IL-6. However, of these proinflammatory cytokines, only IL-6 has consistently been elevated systemically post-burn. In experimental animal models with third-degree

  Skin Burn is a thermal injury caused by biological, chemical, electrical, and physical agents, with local and systemic consequences; it is the most severe form of trauma that has afflicted humanity since time immemorial. Its treatment has improved over time with the scientific revolution. To provide appropriate treatment, the patient's approach must be multidisciplinary; however, in the first instance, the entire body surface must be quantified, not just the percentage but also the depth. Once the clinical classification of burns by depth is understood, these are manifested with characteristic lesions that assist us in recognizing them practically. TNF-α also involves the antimicrobial defenses by activation of neutrophils and monocytes and can induce the secretion of other proinflammatory mediators, including IL-1 and IL-6. However, of these proinflammatory cytokines, only IL-6 has consistently been elevated systemically post-burn. In experimental animal models with third-degree